Covid-19 - lasst ihr euch impfen?
06.12.2020 um 13:08nairobi schrieb:die einzigen Nebenwirkungen dritten Grades die häufiger als 2 % auftraten, waren Erschöpfung mit 3,8 % und Kopfschmerzen mit 2,0 %Das sind typische kurzfistige Nebenwirkungen. Über langfristige Nebenwirkungen ist nichts bekannt.
Es gibt auch offene Fragen was die langfristige Wirksamkeit der neuen Impstoffe betrifft, bzw. warum einige der Impfstoffe eine hohe Wirksamkeit aufweisen (laut Wikipedia)
Scientists were also not clear as to why the novel mRNA COVID-19 vaccines from Moderna and BioNTect/Pfizer have shown potential high efficacy rates of 90 to 95 percent (from their November press releases), when the prior mRNA drug trials on other pathogens (i.e. other than COVID-19), were not so promising and had to be abandoned in the early phases of trials.[29] Virologist Margaret Liu stated that it could be due to the "sheer volume of resources" that went into development, or that the vaccines might be "triggering a nonspecific inflammatory response to the mRNA that could be heightening its specific immune response, given that the modified nucleoside technique reduced inflammation but hasn't eliminated it completely", and that "this may also explain the intense reactions such as aches and fevers reported in some recipients of the mRNA SARS-CoV-2 vaccines" (these fevers were believed to be reactogenic effects from the lipid drug delivery molecules)
In December 2020, Professor Yossi Karko, who oversaw mRNA trials at the Hadassah Medical Center, warned that there were limitations to the data provided to date regarding mRNA vaccines and that the efficacy covered a short period.[30] Peter Doshi, editor of the British Medical Journal, expressed caution over the lack of data outside of press releases, and in particular that, "I previously argued that the trials are studying the wrong endpoint, and for an urgent need to correct course and study more important endpoints like prevention of severe disease and transmission in high-risk people"Wikipedia: RNA vaccine#Efficacy