Die AIDS-Verschwörung
27.03.2011 um 16:32@optimusprime
"In humans, the predictive value of immune activation level on HIV disease course, independent of plasma HIV RNA levels, can be demonstrated even when measured during early infection[47] or before actual seroconversion.[48] Thus, immune activation may be a major determinant of T-cell turnover and CD4 cell depletion in chronic HIV infection[49] both in human and animal hosts. Our results provide further support for additional studies exploring the relative contribution of immune activation to the pathogenesis of immune deterioration in treatment-naive, HIV-infected persons."
47.
Deeks SG, Kitchen CM, Liu L, et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood. 2004;104:942-947.pmid:15117761
48.
Hazenberg MD, Otto SA, van Benthem BH, et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS. 2003;17:1881-1888.pmid:12960820
49.
Sieg SF, Rodriguez B, Asaad R, Jiang W, Bazdar DA, Lederman MM. Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement. J Infect Dis. 2005;192:62-70.pmid:15942895
http://jama.ama-assn.org/content/296/12/1498.full
Was bleibt nun übrig von deiner Behauptung, daß "CD4 keine Auskunft über den Immunstatus gibt"?
"In humans, the predictive value of immune activation level on HIV disease course, independent of plasma HIV RNA levels, can be demonstrated even when measured during early infection[47] or before actual seroconversion.[48] Thus, immune activation may be a major determinant of T-cell turnover and CD4 cell depletion in chronic HIV infection[49] both in human and animal hosts. Our results provide further support for additional studies exploring the relative contribution of immune activation to the pathogenesis of immune deterioration in treatment-naive, HIV-infected persons."
47.
Deeks SG, Kitchen CM, Liu L, et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood. 2004;104:942-947.pmid:15117761
48.
Hazenberg MD, Otto SA, van Benthem BH, et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS. 2003;17:1881-1888.pmid:12960820
49.
Sieg SF, Rodriguez B, Asaad R, Jiang W, Bazdar DA, Lederman MM. Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement. J Infect Dis. 2005;192:62-70.pmid:15942895
http://jama.ama-assn.org/content/296/12/1498.full
Was bleibt nun übrig von deiner Behauptung, daß "CD4 keine Auskunft über den Immunstatus gibt"?